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WDR3 has not been detected as a mutational cancer driver

WDR3
Ensembl id ENSG00000065183
Mutated samples
Coding Sequence 55 (0.8%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all WDR3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 10 2.71
Lung adenocarcinoma No 6 5 1.28
Head and neck squamous cell carcinoma No 4 4 1.07
Bladder carcinoma No 4 3 3.06
Breast carcinoma No 4 3 0.26
Uterine corpus endometrioid carcinoma No 4 3 1.30
Colorectal adenocarcinoma No 3 3 1.31
Lung squamous cell carcinoma No 3 2 1.15
Stomach adenocarcinoma No 2 2 1.24
Hepatocarcinoma No 2 1 1.11
Neuroblastoma No 1 1 0.48
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Prostate adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence