Top
VWA3B has not been detected as a mutational cancer driver

VWA3B
Ensembl id ENSG00000168658
Mutated samples
Coding Sequence 134 (2.0%)
Protein Affecting 111 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all VWA3B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 55 43 11.65
Lung adenocarcinoma No 15 15 3.84
Lung squamous cell carcinoma No 11 9 5.17
Head and neck squamous cell carcinoma No 9 7 1.87
Breast carcinoma No 7 6 0.52
Stomach adenocarcinoma No 6 6 3.73
Uterine corpus endometrioid carcinoma No 5 5 2.17
Bladder carcinoma No 4 4 4.08
Thyroid carcinoma No 4 4 1.24
Renal clear cell carcinoma No 4 3 0.72
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 2 2 1.37
Acute myeloid leukemia No 1 1 0.51
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Diffuse B cell lymphoma No 1 1 4.35
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence