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VEPH1 has not been detected as a mutational cancer driver

VEPH1
Ensembl id ENSG00000197415
Mutated samples
Coding Sequence 97 (1.4%)
Protein Affecting 53 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all VEPH1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 15 9 5.17
Cutaneous melanoma No 12 8 2.17
Head and neck squamous cell carcinoma No 16 7 1.87
Breast carcinoma No 7 6 0.52
Esophageal carcinoma No 6 4 2.74
Lung adenocarcinoma No 6 3 0.77
Stomach adenocarcinoma No 5 3 1.86
Colorectal adenocarcinoma No 5 3 1.31
Hepatocarcinoma No 2 2 2.22
Prostate adenocarcinoma No 2 1 0.41
Bladder carcinoma No 3 1 1.02
Pancreas adenocarcinoma No 2 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Uterine corpus endometrioid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Lower grade glioma No 2 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence