Top
USP34 has not been detected as a mutational cancer driver

USP34
Ensembl id ENSG00000115464
Mutated samples
Coding Sequence 176 (2.6%)
Protein Affecting 121 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all USP34 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 29 20 5.42
Lung squamous cell carcinoma No 24 18 10.34
Breast carcinoma No 19 15 1.31
Lung adenocarcinoma No 12 10 2.56
Stomach adenocarcinoma No 16 10 6.21
Renal clear cell carcinoma No 12 6 1.44
Uterine corpus endometrioid carcinoma No 9 6 2.61
Head and neck squamous cell carcinoma No 9 6 1.60
Serous ovarian adenocarcinoma No 7 5 1.58
Colorectal adenocarcinoma No 5 5 2.18
Bladder carcinoma No 5 4 4.08
Small cell lung carcinoma No 3 3 4.35
Pancreas adenocarcinoma No 2 2 0.93
Thyroid carcinoma No 3 2 0.62
Esophageal carcinoma No 3 2 1.37
Hepatocarcinoma No 3 1 1.11
Acute myeloid leukemia No 1 1 0.51
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 5 1 3.23
Chronic lymphocytic leukemia No 4 1 0.34
Multiple myeloma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence