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USP24 has not been detected as a mutational cancer driver

USP24
Ensembl id ENSG00000162402
Mutated samples
Coding Sequence 93 (1.4%)
Protein Affecting 63 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all USP24 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 11 2.98
Breast carcinoma No 7 7 0.61
Lung squamous cell carcinoma No 10 7 4.02
Uterine corpus endometrioid carcinoma No 11 6 2.61
Lung adenocarcinoma No 7 5 1.28
Renal clear cell carcinoma No 8 5 1.20
Serous ovarian adenocarcinoma No 7 5 1.58
Esophageal carcinoma No 5 5 3.42
Bladder carcinoma No 4 4 4.08
Head and neck squamous cell carcinoma No 6 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Acute myeloid leukemia No 1 1 0.51
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence