IntOGen - UBR5 gene cancer mutations

UBR5 is detected as a mutational cancer driver

UBR5 reports

Methods
Mutation distribution

Gene details

UBR5
Ensembl ID ENSG00000104517 Transcript ID ENST00000520539 Protein ID ENSP00000429084
Cancer types where is driver 5 Cohorts where is driver 6 Mutated samples 25 Mutations 956
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence