Top
UBE2NL has not been detected as a mutational cancer driver

UBE2NL
Ensembl id ENSG00000102069
Mutated samples
Coding Sequence 48 (0.7%)
Protein Affecting 34 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all UBE2NL gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 8 2.17
Lung adenocarcinoma No 5 4 1.02
Lung squamous cell carcinoma No 6 3 1.72
Uterine corpus endometrioid carcinoma No 3 3 1.30
Small cell lung carcinoma No 3 3 4.35
Stomach adenocarcinoma No 2 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 4 2 0.53
Glioblastoma multiforme No 3 2 0.53
Esophageal carcinoma No 3 2 1.37
Breast carcinoma No 1 1 0.09
Non small cell lung carcinoma No 1 1 3.23
Diffuse B cell lymphoma No 1 1 4.35
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence