Top
UAP1 has not been detected as a mutational cancer driver

UAP1
Ensembl id ENSG00000117143
Mutated samples
Coding Sequence 34 (0.5%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all UAP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 3 3 0.77
Breast carcinoma No 4 3 0.26
Cutaneous melanoma No 9 3 0.81
Lung squamous cell carcinoma No 2 2 1.15
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Bladder carcinoma No 2 1 1.02
Stomach adenocarcinoma No 1 1 0.62
Diffuse B cell lymphoma No 1 1 4.35
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence