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TUBA4A has not been detected as a mutational cancer driver

TUBA4A
Ensembl id ENSG00000127824
Mutated samples
Coding Sequence 74 (1.1%)
Protein Affecting 24 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TUBA4A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 6 1.63
Lung adenocarcinoma No 8 3 0.77
Uterine corpus endometrioid carcinoma No 10 3 1.30
Serous ovarian adenocarcinoma No 4 3 0.95
Renal clear cell carcinoma No 2 2 0.48
Prostate adenocarcinoma No 2 1 0.41
Breast carcinoma No 2 1 0.09
Lung squamous cell carcinoma No 5 1 0.57
Chronic lymphocytic leukemia No 3 1 0.34
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 7 1 0.27
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Stomach adenocarcinoma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence