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TSC2 × Bladder Urothelial Carcinoma ×

TSC2 is detected as a mutational cancer driver in Bladder Urothelial Carcinoma

TSC2 reports in Bladder Urothelial Carcinoma (BLCA)

Cancer type details
Bladder Urothelial Carcinoma
Cohorts 8
Samples 905
Mutations 6,585,575
Driver genes 89
Gene details
TSC2
Ensembl ID ENSG00000103197
Transcript ID ENST00000219476
Protein ID ENSP00000219476
Cohorts where is driver 1
Mutated samples 3
Mutated samples (%) 0.33
Mutations 46
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence