IntOGen - TRRAP gene cancer mutations

TRRAP is detected as a mutational cancer driver

TRRAP reports

Methods
Mutation distribution

Gene details

TRRAP
Ensembl ID ENSG00000196367 Transcript ID ENST00000359863 Protein ID ENSP00000352925
Cancer types where is driver 10 Cohorts where is driver 11 Mutated samples 199 Mutations 1,423
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence