Top
TRMT2B has not been detected as a mutational cancer driver

TRMT2B
Ensembl id ENSG00000188917
Mutated samples
Coding Sequence 36 (0.5%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TRMT2B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 6 6 0.52
Lung adenocarcinoma No 5 5 1.28
Cutaneous melanoma No 8 5 1.36
Lung squamous cell carcinoma No 3 2 1.15
Stomach adenocarcinoma No 2 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Renal clear cell carcinoma No 2 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence