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TRAPPC8 has not been detected as a mutational cancer driver

TRAPPC8
Ensembl id ENSG00000153339
Mutated samples
Coding Sequence 70 (1.0%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TRAPPC8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 9 2.44
Breast carcinoma No 9 8 0.70
Renal clear cell carcinoma No 6 5 1.20
Serous ovarian adenocarcinoma No 6 5 1.58
Lung adenocarcinoma No 5 4 1.02
Lung squamous cell carcinoma No 4 4 2.30
Glioblastoma multiforme No 4 4 1.06
Stomach adenocarcinoma No 5 3 1.86
Head and neck squamous cell carcinoma No 4 3 0.80
Bladder carcinoma No 2 2 2.04
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 2 1 0.82
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence