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TRAK2 has not been detected as a mutational cancer driver

TRAK2
Ensembl id ENSG00000115993
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TRAK2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 6 1.63
Breast carcinoma No 6 5 0.44
Lung squamous cell carcinoma No 5 5 2.87
Stomach adenocarcinoma No 5 5 3.11
Lung adenocarcinoma No 4 4 1.02
Uterine corpus endometrioid carcinoma No 2 2 0.87
Glioblastoma multiforme No 3 2 0.53
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 1 1 1.02
Non small cell lung carcinoma No 2 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 1 1 0.27
Esophageal carcinoma No 2 1 0.68
Pylocytic astrocytoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence