Top
TP53I3 has not been detected as a mutational cancer driver

TP53I3
Ensembl id ENSG00000115129
Mutated samples
Coding Sequence 21 (0.3%)
Protein Affecting 13 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TP53I3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 5 3 0.81
Lung adenocarcinoma No 2 2 0.51
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 3 2 0.48
Colorectal adenocarcinoma No 2 2 0.87
Breast carcinoma No 2 1 0.09
Esophageal carcinoma No 1 1 0.68
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence