Gene details
| TOP2A |
|---|
|
Ensembl ID
ENSG00000131747
Transcript ID ENST00000423485 Protein ID ENSP00000411532 |
|
Cancer types where is driver
1
Cohorts where is driver 1 Mutated samples 6 Mutations 421 |
| Mode of action Activating |
| Known driver False |
Method signals per Cancer Type
| Cancer type | Methods | Samples | Samples (%) |
|---|
ClustL
HotMAPS
smRegions
Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed
mutations along the protein sequence.
| Mutation (GRCh38) | Protein Position | Samples | Consequence |
|---|