IntOGen - TNFRSF14 gene cancer mutations

TNFRSF14 is detected as a mutational cancer driver

TNFRSF14 reports

Methods
Mutation distribution

Gene details

TNFRSF14
Ensembl ID ENSG00000157873 Transcript ID ENST00000355716 Protein ID ENSP00000347948
Cancer types where is driver 4 Cohorts where is driver 6 Mutated samples 70 Mutations 171
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence