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TMEM198 has not been detected as a mutational cancer driver

TMEM198
Ensembl id ENSG00000188760
Mutated samples
Coding Sequence 80 (1.2%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TMEM198 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 20 6 1.63
Stomach adenocarcinoma No 7 5 3.11
Renal clear cell carcinoma No 3 3 0.72
Head and neck squamous cell carcinoma No 10 3 0.80
Esophageal carcinoma No 4 3 2.05
Colorectal adenocarcinoma No 3 2 0.87
Prostate adenocarcinoma No 2 1 0.41
Lung adenocarcinoma No 5 1 0.26
Bladder carcinoma No 3 1 1.02
Chronic lymphocytic leukemia No 1 1 0.34
Serous ovarian adenocarcinoma No 2 1 0.32
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Breast carcinoma No 4 0 0.00
Medulloblastoma No 2 0 0.00
Lung squamous cell carcinoma No 6 0 0.00
Neuroblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 3 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence