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THRB has not been detected as a mutational cancer driver

THRB
Ensembl id ENSG00000151090
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 29 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all THRB gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 17 4.61
Lung adenocarcinoma No 2 2 0.51
Colorectal adenocarcinoma No 2 2 0.87
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 2 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Pancreas adenocarcinoma No 1 1 0.47
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 3 1 0.62
Head and neck squamous cell carcinoma No 1 1 0.27
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence