Top
THEMIS2 has not been detected as a mutational cancer driver

THEMIS2
Ensembl id ENSG00000130775
Mutated samples
Coding Sequence 22 (0.3%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all THEMIS2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 3 2 0.87
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 1 1 0.09
Cutaneous melanoma No 3 1 0.27
Chronic lymphocytic leukemia No 1 1 0.34
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Stomach adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence