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THADA has not been detected as a mutational cancer driver

THADA
Ensembl id ENSG00000115970
Mutated samples
Coding Sequence 145 (2.1%)
Protein Affecting 75 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all THADA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 38 23 6.23
Lung adenocarcinoma No 12 9 2.30
Lung squamous cell carcinoma No 15 9 5.17
Uterine corpus endometrioid carcinoma No 11 6 2.61
Renal clear cell carcinoma No 8 5 1.20
Head and neck squamous cell carcinoma No 15 4 1.07
Bladder carcinoma No 7 3 3.06
Breast carcinoma No 7 3 0.26
Glioblastoma multiforme No 5 3 0.79
Neuroblastoma No 3 2 0.95
Multiple myeloma No 2 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 3 1 1.11
Serous ovarian adenocarcinoma No 3 1 0.32
Stomach adenocarcinoma No 2 1 0.62
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 4 1 0.68
Chronic lymphocytic leukemia No 4 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence