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TGM4 has not been detected as a mutational cancer driver

TGM4
Ensembl id ENSG00000163810
Mutated samples
Coding Sequence 79 (1.2%)
Protein Affecting 59 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TGM4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 18 4.88
Lung adenocarcinoma No 14 10 2.56
Head and neck squamous cell carcinoma No 7 6 1.60
Breast carcinoma No 4 4 0.35
Lung squamous cell carcinoma No 5 4 2.30
Colorectal adenocarcinoma No 5 4 1.75
Bladder carcinoma No 3 3 3.06
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 2 2 1.24
Hepatocarcinoma No 1 1 1.11
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Prostate adenocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence