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TGIF2LX has not been detected as a mutational cancer driver

TGIF2LX
Ensembl id ENSG00000153779
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TGIF2LX gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 17 11 2.81
Lung squamous cell carcinoma No 10 9 5.17
Cutaneous melanoma No 12 6 1.63
Bladder carcinoma No 3 3 3.06
Stomach adenocarcinoma No 4 3 1.86
Breast carcinoma No 2 2 0.17
Head and neck squamous cell carcinoma No 3 2 0.53
Esophageal carcinoma No 2 2 1.37
Renal clear cell carcinoma No 1 1 0.24
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 1 1 0.59
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 3 1 0.26
Uterine corpus endometrioid carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence