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TENM1 has not been detected as a mutational cancer driver

TENM1
Ensembl id ENSG00000009694
Mutated samples
Coding Sequence 338 (5.0%)
Protein Affecting 234 (3.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TENM1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 88 64 17.34
Lung adenocarcinoma No 38 25 6.39
Head and neck squamous cell carcinoma No 22 20 5.33
Breast carcinoma No 23 18 1.57
Lung squamous cell carcinoma No 25 16 9.20
Uterine corpus endometrioid carcinoma No 18 14 6.09
Colorectal adenocarcinoma No 17 14 6.11
Serous ovarian adenocarcinoma No 11 11 3.48
Stomach adenocarcinoma No 17 10 6.21
Renal clear cell carcinoma No 11 7 1.68
Small cell lung carcinoma No 6 6 8.70
Glioblastoma multiforme No 5 5 1.32
Bladder carcinoma No 6 4 4.08
Multiple myeloma No 4 4 5.80
Esophageal carcinoma No 5 4 2.74
Lower grade glioma No 6 3 1.78
Chronic lymphocytic leukemia No 16 2 0.69
Hepatocarcinoma No 4 1 1.11
Medulloblastoma No 3 1 0.48
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 2 1 0.31
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 2 1 3.23
Acute lymphocytic leukemia No 2 1 0.82
Prostate adenocarcinoma No 2 0 0.00
Pylocytic astrocytoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence