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TEKT4 has not been detected as a mutational cancer driver

TEKT4
Ensembl id ENSG00000163060
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 33 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TEKT4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 7 4 2.30
Cutaneous melanoma No 9 4 1.08
Lung adenocarcinoma No 3 3 0.77
Renal clear cell carcinoma No 3 3 0.72
Stomach adenocarcinoma No 4 3 1.86
Head and neck squamous cell carcinoma No 3 3 0.80
Glioblastoma multiforme No 3 3 0.79
Neuroblastoma No 3 2 0.95
Uterine corpus endometrioid carcinoma No 3 2 0.87
Esophageal carcinoma No 2 2 1.37
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 1 1 0.09
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence