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TCHHL1 has not been detected as a mutational cancer driver

TCHHL1
Ensembl id ENSG00000182898
Mutated samples
Coding Sequence 106 (1.6%)
Protein Affecting 84 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TCHHL1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 55 47 12.74
Lung adenocarcinoma No 12 9 2.30
Breast carcinoma No 7 6 0.52
Bladder carcinoma No 4 4 4.08
Lung squamous cell carcinoma No 6 3 1.72
Esophageal carcinoma No 4 3 2.05
Renal clear cell carcinoma No 2 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Head and neck squamous cell carcinoma No 2 2 0.53
Hepatocarcinoma No 2 1 1.11
Acute myeloid leukemia No 1 1 0.51
Uterine corpus endometrioid carcinoma No 1 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Stomach adenocarcinoma No 2 1 0.62
Small cell lung carcinoma No 2 1 1.45
Chronic lymphocytic leukemia No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence