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TCHH has not been detected as a mutational cancer driver

TCHH
Ensembl id ENSG00000159450
Mutated samples
Coding Sequence 191 (2.8%)
Protein Affecting 141 (2.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TCHH gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 37 26 7.05
Lung adenocarcinoma No 21 16 4.09
Stomach adenocarcinoma No 20 16 9.94
Glioblastoma multiforme No 18 15 3.96
Breast carcinoma No 15 11 0.96
Uterine corpus endometrioid carcinoma No 11 7 3.04
Lung squamous cell carcinoma No 6 6 3.45
Head and neck squamous cell carcinoma No 10 6 1.60
Esophageal carcinoma No 6 6 4.11
Bladder carcinoma No 10 5 5.10
Renal clear cell carcinoma No 8 5 1.20
Neuroblastoma No 5 5 2.38
Colorectal adenocarcinoma No 5 5 2.18
Lower grade glioma No 5 4 2.37
Prostate adenocarcinoma No 4 3 1.23
Serous ovarian adenocarcinoma No 3 2 0.63
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 3 1 0.31
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence