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TBX22 has not been detected as a mutational cancer driver

TBX22
Ensembl id ENSG00000122145
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 63 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all TBX22 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 14 14 3.58
Cutaneous melanoma No 14 11 2.98
Head and neck squamous cell carcinoma No 12 9 2.40
Lung squamous cell carcinoma No 8 6 3.45
Breast carcinoma No 7 5 0.44
Small cell lung carcinoma No 5 4 5.80
Colorectal adenocarcinoma No 6 4 1.75
Stomach adenocarcinoma No 2 2 1.24
Glioblastoma multiforme No 6 2 0.53
Hepatocarcinoma No 1 1 1.11
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Esophageal carcinoma No 1 1 0.68
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence