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STON1 has not been detected as a mutational cancer driver

STON1
Ensembl id ENSG00000243244
Mutated samples
Coding Sequence 75 (1.1%)
Protein Affecting 53 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all STON1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 31 22 5.96
Esophageal carcinoma No 7 7 4.79
Lung squamous cell carcinoma No 6 5 2.87
Lung adenocarcinoma No 5 3 0.77
Breast carcinoma No 4 3 0.26
Neuroblastoma No 2 2 0.95
Small cell lung carcinoma No 3 2 2.90
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 2 1 0.24
Non small cell lung carcinoma No 3 1 3.23
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 1 1 0.27
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence