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STARD8 has not been detected as a mutational cancer driver

STARD8
Ensembl id ENSG00000130052
Mutated samples
Coding Sequence 80 (1.2%)
Protein Affecting 58 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all STARD8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 12 3.25
Lung adenocarcinoma No 11 10 2.56
Breast carcinoma No 13 10 0.87
Lung squamous cell carcinoma No 10 8 4.60
Stomach adenocarcinoma No 5 5 3.11
Uterine corpus endometrioid carcinoma No 4 3 1.30
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 2 1 0.41
Bladder carcinoma No 2 1 1.02
Neuroblastoma No 1 1 0.48
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence