Top
STAB1 has not been detected as a mutational cancer driver

STAB1
Ensembl id ENSG00000010327
Mutated samples
Coding Sequence 184 (2.7%)
Protein Affecting 96 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all STAB1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 67 40 10.84
Stomach adenocarcinoma No 16 8 4.97
Lung adenocarcinoma No 11 7 1.79
Bladder carcinoma No 12 7 7.14
Breast carcinoma No 10 5 0.44
Lung squamous cell carcinoma No 10 5 2.87
Glioblastoma multiforme No 11 5 1.32
Uterine corpus endometrioid carcinoma No 11 4 1.74
Head and neck squamous cell carcinoma No 11 4 1.07
Medulloblastoma No 3 2 0.95
Thyroid carcinoma No 3 2 0.62
Non small cell lung carcinoma No 2 2 6.45
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 3 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Esophageal carcinoma No 6 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence