Top
SRRM1 has not been detected as a mutational cancer driver

SRRM1
Ensembl id ENSG00000133226
Mutated samples
Coding Sequence 55 (0.8%)
Protein Affecting 39 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SRRM1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 8 2.17
Uterine corpus endometrioid carcinoma No 4 4 1.74
Breast carcinoma No 5 3 0.26
Lung squamous cell carcinoma No 3 3 1.72
Stomach adenocarcinoma No 5 3 1.86
Head and neck squamous cell carcinoma No 3 3 0.80
Lung adenocarcinoma No 3 2 0.51
Medulloblastoma No 2 2 0.95
Serous ovarian adenocarcinoma No 2 2 0.63
Colorectal adenocarcinoma No 2 2 0.87
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 2 1 0.24
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Neuroblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence