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SRPX has not been detected as a mutational cancer driver

SRPX
Ensembl id ENSG00000101955
Mutated samples
Coding Sequence 39 (0.6%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SRPX gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 5 4 0.35
Cutaneous melanoma No 5 4 1.08
Uterine corpus endometrioid carcinoma No 5 4 1.74
Lung adenocarcinoma No 4 3 0.77
Lung squamous cell carcinoma No 3 2 1.15
Small cell lung carcinoma No 3 2 2.90
Head and neck squamous cell carcinoma No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Renal clear cell carcinoma No 1 1 0.24
Chronic lymphocytic leukemia No 1 1 0.34
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Bladder carcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence