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SRBD1 has not been detected as a mutational cancer driver

SRBD1
Ensembl id ENSG00000068784
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 37 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SRBD1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 8 2.17
Lung adenocarcinoma No 6 6 1.53
Breast carcinoma No 6 4 0.35
Lung squamous cell carcinoma No 6 4 2.30
Small cell lung carcinoma No 3 3 4.35
Bladder carcinoma No 4 2 2.04
Renal clear cell carcinoma No 5 2 0.48
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Lower grade glioma No 1 1 0.59
Head and neck squamous cell carcinoma No 1 1 0.27
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Stomach adenocarcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence