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SPRR3 is detected as a mutational cancer driver in 1 cancer type: Lung adenocarcinoma

SPRR3
Ensembl id ENSG00000163209
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 17 (0.3%)
Mode of action Activating
Known driver No
Cancer type Signals (Biases)
LUAD R
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SPRR3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Yes 6 2 0.51
Cutaneous melanoma No 16 11 2.98
Prostate adenocarcinoma No 3 1 0.41
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 1 1 0.27
Breast carcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence