Top
SPATA5 has not been detected as a mutational cancer driver

SPATA5
Ensembl id ENSG00000145375
Mutated samples
Coding Sequence 38 (0.6%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SPATA5 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 6 1.53
Head and neck squamous cell carcinoma No 5 4 1.07
Cutaneous melanoma No 7 3 0.81
Stomach adenocarcinoma No 3 3 1.86
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 2 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Small cell lung carcinoma No 1 1 1.45
Acute lymphocytic leukemia No 1 1 0.82
Lung squamous cell carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence