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SPATA16 has not been detected as a mutational cancer driver

SPATA16
Ensembl id ENSG00000144962
Mutated samples
Coding Sequence 91 (1.3%)
Protein Affecting 66 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SPATA16 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 37 26 7.05
Lung adenocarcinoma No 8 7 1.79
Head and neck squamous cell carcinoma No 9 7 1.87
Lung squamous cell carcinoma No 7 6 3.45
Breast carcinoma No 4 3 0.26
Stomach adenocarcinoma No 3 3 1.86
Chronic lymphocytic leukemia No 6 2 0.69
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 2 1 0.32
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence