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SP140L has not been detected as a mutational cancer driver

SP140L
Ensembl id ENSG00000185404
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SP140L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 15 4.07
Lung adenocarcinoma No 4 3 0.77
Thyroid carcinoma No 2 2 0.62
Head and neck squamous cell carcinoma No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Colorectal adenocarcinoma No 3 1 0.44
Glioblastoma multiforme No 1 1 0.26
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence