SOS1 mutations in 1 Glioblastoma multiforme project possibly contribute to the detection of the gene in the PAN-cancer anlaysis:

Glioblastoma multiforme
Projects 2
379 Samples
Coding sequence mutations (CSMs)
in driver genes 842
in all genes 34259
Protein affecting mutations (PAMs)
in driver genes 766
in all genes 17598
Ensembl id ENSG00000115904
Mutated samples
Coding Sequence 4 (1.1%)
Protein Affecting 4 (1.1%)
Mode of action Activating
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Glioblastoma multiforme projects in all SOS1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Glioblastoma multiforme TCGA Yes 3 3 0.79
Glioblastoma multiforme Johns Hopkins University No 1 1 0.26
The mutations needle plot shows the distribution of the observed SOS1 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification