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SMARCA1 is detected as a mutational cancer driver in 1 cancer type: Prostate adenocarcinoma

SMARCA1
Ensembl id ENSG00000102038
Mutated samples
Coding Sequence 75 (1.1%)
Protein Affecting 50 (0.7%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
PRAD F
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SMARCA1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Prostate adenocarcinoma Yes 5 5 2.06
Breast carcinoma No 9 8 0.70
Uterine corpus endometrioid carcinoma No 12 8 3.48
Cutaneous melanoma No 14 7 1.90
Lung squamous cell carcinoma No 7 6 3.45
Lung adenocarcinoma No 5 3 0.77
Colorectal adenocarcinoma No 3 3 1.31
Serous ovarian adenocarcinoma No 4 2 0.63
Head and neck squamous cell carcinoma No 3 2 0.53
Hepatocarcinoma No 1 1 1.11
Thyroid carcinoma No 2 1 0.31
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 2 1 0.68
Non small cell lung carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence