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SLITRK4 has not been detected as a mutational cancer driver

SLITRK4
Ensembl id ENSG00000179542
Mutated samples
Coding Sequence 112 (1.6%)
Protein Affecting 87 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLITRK4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 21 5.69
Lung adenocarcinoma No 19 17 4.35
Head and neck squamous cell carcinoma No 13 13 3.47
Lung squamous cell carcinoma No 9 7 4.02
Uterine corpus endometrioid carcinoma No 6 5 2.17
Breast carcinoma No 4 4 0.35
Colorectal adenocarcinoma No 5 4 1.75
Esophageal carcinoma No 3 3 2.05
Prostate adenocarcinoma No 2 2 0.82
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 4 2 1.24
Glioblastoma multiforme No 4 2 0.53
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 2 1 0.24
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 2 1 0.34
Hepatocarcinoma No 2 0 0.00
Bladder carcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence