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SLITRK3 has not been detected as a mutational cancer driver

SLITRK3
Ensembl id ENSG00000121871
Mutated samples
Coding Sequence 172 (2.5%)
Protein Affecting 126 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLITRK3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 46 30 8.13
Lung squamous cell carcinoma No 30 24 13.79
Head and neck squamous cell carcinoma No 23 16 4.27
Lung adenocarcinoma No 21 15 3.84
Uterine corpus endometrioid carcinoma No 11 9 3.91
Breast carcinoma No 9 6 0.52
Serous ovarian adenocarcinoma No 6 5 1.58
Colorectal adenocarcinoma No 5 4 1.75
Thyroid carcinoma No 3 3 0.93
Small cell lung carcinoma No 3 3 4.35
Chronic lymphocytic leukemia No 2 2 0.69
Stomach adenocarcinoma No 3 2 1.24
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Medulloblastoma No 1 1 0.48
Pancreas adenocarcinoma No 2 1 0.47
Renal clear cell carcinoma No 2 1 0.24
Lower grade glioma No 1 1 0.59
Diffuse B cell lymphoma No 2 1 4.35
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence