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SLC9C2 has not been detected as a mutational cancer driver

SLC9C2
Ensembl id ENSG00000162753
Mutated samples
Coding Sequence 124 (1.8%)
Protein Affecting 105 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC9C2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 58 51 13.82
Lung adenocarcinoma No 14 11 2.81
Stomach adenocarcinoma No 10 8 4.97
Lung squamous cell carcinoma No 7 5 2.87
Head and neck squamous cell carcinoma No 6 5 1.33
Uterine corpus endometrioid carcinoma No 4 4 1.74
Small cell lung carcinoma No 4 4 5.80
Colorectal adenocarcinoma No 3 3 1.31
Glioblastoma multiforme No 3 3 0.79
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 2 2 0.48
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Breast carcinoma No 2 1 0.09
Chronic lymphocytic leukemia No 2 1 0.34
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 2 1 0.32
Hepatocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence