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SLC9A9 has not been detected as a mutational cancer driver

SLC9A9
Ensembl id ENSG00000181804
Mutated samples
Coding Sequence 92 (1.4%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC9A9 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 15 4.07
Lung adenocarcinoma No 12 9 2.30
Lung squamous cell carcinoma No 11 7 4.02
Breast carcinoma No 4 3 0.26
Stomach adenocarcinoma No 4 3 1.86
Renal clear cell carcinoma No 4 2 0.48
Uterine corpus endometrioid carcinoma No 3 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 3 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 3 2 0.53
Thyroid carcinoma No 1 1 0.31
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 5 0 0.00
Non small cell lung carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence