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SLC9A2 has not been detected as a mutational cancer driver

SLC9A2
Ensembl id ENSG00000115616
Mutated samples
Coding Sequence 110 (1.6%)
Protein Affecting 72 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC9A2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 54 34 9.21
Lung adenocarcinoma No 10 7 1.79
Breast carcinoma No 10 7 0.61
Lung squamous cell carcinoma No 4 4 2.30
Glioblastoma multiforme No 4 4 1.06
Stomach adenocarcinoma No 4 3 1.86
Uterine corpus endometrioid carcinoma No 2 2 0.87
Chronic lymphocytic leukemia No 4 2 0.69
Head and neck squamous cell carcinoma No 5 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 3 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 2 1 0.48
Lower grade glioma No 1 1 0.59
Esophageal carcinoma No 2 1 0.68
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence