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SLC6A9 has not been detected as a mutational cancer driver

SLC6A9
Ensembl id ENSG00000196517
Mutated samples
Coding Sequence 59 (0.9%)
Protein Affecting 29 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC6A9 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 18 7 1.90
Stomach adenocarcinoma No 4 4 2.48
Lung adenocarcinoma No 7 3 0.77
Breast carcinoma No 4 3 0.26
Uterine corpus endometrioid carcinoma No 6 3 1.30
Bladder carcinoma No 4 2 2.04
Head and neck squamous cell carcinoma No 6 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Acute myeloid leukemia No 2 1 0.51
Thyroid carcinoma No 2 1 0.31
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence