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SLC4A7 has not been detected as a mutational cancer driver

SLC4A7
Ensembl id ENSG00000033867
Mutated samples
Coding Sequence 58 (0.9%)
Protein Affecting 44 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC4A7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 10 2.71
Breast carcinoma No 5 5 0.44
Head and neck squamous cell carcinoma No 4 4 1.07
Glioblastoma multiforme No 4 4 1.06
Lung adenocarcinoma No 4 3 0.77
Uterine corpus endometrioid carcinoma No 3 3 1.30
Serous ovarian adenocarcinoma No 4 3 0.95
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 3 2 0.48
Stomach adenocarcinoma No 2 2 1.24
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Esophageal carcinoma No 1 1 0.68
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence