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SLC4A3 has not been detected as a mutational cancer driver

SLC4A3
Ensembl id ENSG00000114923
Mutated samples
Coding Sequence 81 (1.2%)
Protein Affecting 54 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC4A3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 15 4.07
Lung adenocarcinoma No 10 8 2.05
Stomach adenocarcinoma No 6 6 3.73
Head and neck squamous cell carcinoma No 8 5 1.33
Breast carcinoma No 4 3 0.26
Prostate adenocarcinoma No 2 2 0.82
Lung squamous cell carcinoma No 5 2 1.15
Renal clear cell carcinoma No 4 2 0.48
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 4 2 1.37
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Hepatocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence