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SLC4A10 has not been detected as a mutational cancer driver

SLC4A10
Ensembl id ENSG00000144290
Mutated samples
Coding Sequence 185 (2.7%)
Protein Affecting 96 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC4A10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 70 27 7.32
Lung adenocarcinoma No 18 13 3.32
Lung squamous cell carcinoma No 19 13 7.47
Head and neck squamous cell carcinoma No 10 7 1.87
Bladder carcinoma No 5 5 5.10
Breast carcinoma No 6 5 0.44
Renal clear cell carcinoma No 6 4 0.96
Esophageal carcinoma No 6 4 2.74
Chronic lymphocytic leukemia No 13 3 1.03
Glioblastoma multiforme No 4 3 0.79
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Acute lymphocytic leukemia No 2 2 1.64
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 2 1 0.48
Non small cell lung carcinoma No 3 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 8 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence