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SLC45A1 has not been detected as a mutational cancer driver

SLC45A1
Ensembl id ENSG00000162426
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all SLC45A1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 7 1.90
Lung adenocarcinoma No 6 4 1.02
Breast carcinoma No 5 4 0.35
Lung squamous cell carcinoma No 3 3 1.72
Bladder carcinoma No 3 2 2.04
Stomach adenocarcinoma No 5 2 1.24
Esophageal carcinoma No 2 2 1.37
Uterine corpus endometrioid carcinoma No 2 1 0.43
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 2 1 0.34
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 3 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence